A pre-specified phylogenetic comparison across thousands of species finds niche safety strongly associated with mammalian lifespan while environmental variability shows no detectable independent effect. A parallel result emerged for metabolism. A basal-metabolic-rate correlate of lifespan, a recurring theme in ageing…
Every year, tens of millions of mammograms are performed worldwide, and many of them contain a quiet clue about a woman's heart health that goes unreported. Breast arterial calcifications, the calcium deposits that build up in the walls of the…
The findings support the clinical benefits of delandistrogene moxeparvovec in patients with Duchenne muscular dystrophy (DMD). Patients with Duchenne muscular dystrophy (DMD) aged 8 and 9 years experienced significant functional benefits with delandistrogene moxeparvovec-rokl (Elevidys; Sarepta Therapeutics) in part 2 of the EMBARK study (NCT05096221), according…
WVE-N531 demonstrated statistically significant improvements in muscle biopsy measures and functional measures in patients with Duchenne muscular dystrophy (DMD) in the phase 2 FORWARD-53 trial.
An FDA committee voted 9-3 that available data did not provide substantial evidence of effectiveness for deramiocel in DMD. Long-Term Data Reinforce Givinostat Efficacy, Safety in DMD DYNE-251 Granted FDA Breakthrough Therapy Designation for DMD FDA Recommends Sarepta Resume DMD Gene Therapy…
CIDRAP Information Hub to promote evidence-based public health information and help users navigate a world of misinformation and disinformation. Researchers from the University of Minnesota found that drinking kombucha was associated with reduced anxiety and depressive-like behaviors in mice. For…
A proof-of-concept study shows that collagen features quantified from routine Trichrome-stained breast histopathology slides agree significantly with SHG microscopy measurements, particularly for collagen area and fibre alignment. Before any comparison, the team confirmed that SHG signals could be consistently detected…
A scoping review of research from 2017 through July 2025 found growing use of the Theoretical Framework of Acceptability alongside variable methods and insufficient reporting detail.
Telehealth and Home Video Prove Reliable for Assessing Duchenne Muscular Dystrophy Researchers used a video platform compliant with 21 Code of Federal Regulations Part 11 to compare live telehealth with asynchronous at-home videos and to compare live with recorded telehealth scoring. NSAA-certified…
Why Lifespans Differ Across Species The reproduction -- survival trade-off Producing offspring requires enormous biological investment. Pregnancy, nursing, sperm production, courtship behavior, and parental care all consume large amounts of energy. Even outside of active breeding, sex hormones such as testosterone…
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